www.BuyersGuideChem.com - the comprehensive directory of chemicals and chemical suppliers

Melatonin

is a Star Product of
BuyersGuideChem


General information
Registration name: Melatonin
Other product names:
N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
N-Acetyl-5-methoxytryptamine
 
CAS number 73-31-4 Structure
EINECS: 200-797-7
Formula: C13H16N2O2

Detailed information on the Star Product
Melatonin Synonyms:
N-Acetyl-5-methoxytryptamine;
3-(N-Acetyl-2-aminoethyl)-5-methoxyindole
Molecular Formula: C13H16N2O2
Molecular Weight: 232.28
Assay: ≥99%
Apperance: White crystalline

Melatonin is a hormone secreted by the pineal gland in the brain that helps regulate other hormones and maintains the body's circadian rhythm. The circadian rhythm is an internal 24-hour time-keeping system that plays a critical role in determining when we fall asleep and when we wake up. Darkness stimulates the production of melatonin while light suppresses its activity. Exposure to excessive light in the evening or too little light during the day can disrupt the body’s normal melatonin cycles. For example, jet lag, shift work, and poor vision can disrupt melatonin cycles. In addition, some experts claim that exposure to low-frequency electromagnetic fields (common in household appliances) may disrupt normal cycles and production of melatonin.

Melatonin also helps control the timing and release of female reproductive hormones. It helps determine when menstruation begins, the frequency and duration of menstrual cycles, and when menstruation ends (menopause).

Function of Melatonin
1. Studies suggest that melatonin supplements may help induce sleep in people with disrupted circadian rhythms (such as those suffering from jet lag or poor vision or those who work the night shift) and those with low melatonin levels (such as some elderly and individuals with schizophrenia). A review of clinical studies suggests that melatonin supplements may help prevent jet lag, particularly in people who cross five or more time zones.

2. A few clinical studies suggest that when taken for short periods of time (days to weeks) melatonin is significantly more effective than a placebo, in decreasing the amount of time required to fall asleep, increasing the number of sleeping hours, and boosting daytime alertness.

3. Multiple human studies have measured the effects of melatonin supplements on sleep in healthy individuals. A wide range of doses has been used, often taken by mouth 30 - 60 minutes prior to sleep time. A study of 334 people aged 55 and older found that prolonged-release melatonin produced significant and clinically meaningful improvements in sleep quality, morning alertness, sleep onset latency, and quality of life in primary insomnia patients aged 55 years and over.

>> Ask for an offer


Star Picture

© Copyright 1996 to 2024 by Netvertise GmbH. All rights reserved